In Person Ride: Sunday 14, 2025
Location: Daniel Boone Homestead
The Breakthrough Challenge was founded in 2013. Our goal is to raise funds supporting breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center by uniting for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley.
There are three ride options based on length of miles. We also virtual events if you wish to participate in running, spinning, walking and biking at any location. Please click on the ride option below and sign-up.
*Please be prepared to have wheels on the ground and ready to ride by the designated start time.
Event Registration (Click Below)
Virtual Events
Venue Details
Post Ride Lunch 11:15 am to 2:00 pm